Overview

The SentroPAT Compact is a flexible, rugged NIR analyzer designed for non-destructive online monitoring of powders and granules in pharmaceutical and food manufacturing. 
This system provides valuable process insight during process development and reliable process information when deployed in commercial operation. As our newest system, the 
SentroPAT compact benefits from technological and design innovations built on Sentronic's 30+ years of supporting in-line spectroscopic analysis.

  • Compact, all-in-one NIR process analyzer
  • Wide spectral range (1100-1900 nm)
  • High stability due to internal intensity and wavelength standards
  • Just one cable (power-over-Ethernet) connection required and 
    no fiberoptic cables need for installation
  • Easy-to-use and field-proven software control

Applications

While the capabilities of the SentroPAT system could benefit a wide range of industries, we have chosen to focus primarily on the pharmaceutical sector, particularly in the manufacturing of oral solid dosage forms. As a result, nine of the world's top ten pharmaceutical companies have chosen Sentronic as a trusted partner for their process analytical needs. The SentroPAT Compact as the latest adddition to the powerful SentroPAT family perfectly extends this capabilities and is compatbile to well known and established applications.

Tablet press feed frame
Sentronic has been involved in the earliest developments of PAT for tablet press feed frame, here in applications back in 2014.
Commercial Scale in Tablet Press Feed Frame
Numerous installations on tablet presses of all major brands are existent today.
Blend uniformity in various CDC setups
Sentronic systems are empowering inline control of commercial continuous direct compression lines, here used in combination with the EXPO Process TASO sampling interface.
High Shear Wet Granulation
The improvement of consistency in this unit operatoin using the Sentronic NIR solutions has significant potential and is underutilised today. In comparison to just moisture or particle size analyzers, NIR provides a unique combination of physical and chemical information.

Technical Data

SentroPAT Compact
Software Interfaces
Spectrometer Type Diode Array (512 pixel InGaAs linear array)
Wavelength range 1100-1900nm
Spectral resolution NMT 10nm
Wavelength accuracy +-1nm over full specification range
Wavelength Reproducibility < 0.2nm
Photometric Linearity Conforms to USP<1856> and EP 2.2.40 requirements
System noise Conforms to USP<1856> and EP 2.2.40 requirements
Embedded Controller i.MX8 MM processor / Linux
Connections Power over ethernet IEEE 802.3at (PoE+)
Housing Dimensions 160 x 85 x 80mm
Shaft Diameter 19mm
Shaft lengths 65, 100, 170, 200, and 300mm
Operating conditions 10° … 30°C 10% … 90% relative humidity
Software SentroSuite GMP on external PC
Validation Software integrated validation routines according USP<1856>, EP2.2.40
Chemometric Interfaces SIMCA, VektorDirektor
OPC-UA on external PC
OPC-DA based on dedicated remote server
Integrated to PAT management systems SIPAT, synTQ, ProaXesS
SDK A software developer kit is available to directly develop interfaces using TCP/IP protocol
Download data sheet

Need personal assistance? We’re here to help!

Looking for more tailored support? Don’t hesitate to reach out—we’re happy to assist you! Or explore our knowledge base for in-depth insights and technical details.

Frequently Asked Questions

Learn more about the SentroPat FO and its wide range of applications in pharmaceutical manufacturing. This section provides additional insights and detailed information to help you fully understand the potential and versatility of our cutting-edge sensor technology.

How long do the NIR sources last in the SentroPAT Compact?

Expected that they last for the lifecycle of the instrument. Lamps no longer need to be changed per PM

Can I use the SentroPAT Compact with a sapphire process window for product containment?

It is possible to do, albeit it results in some loss of signal-to-noise. It further introduces a risk of interference effects between the process sapphire and the probe window. This can be easily avoided by enuring a small gap between the two sapphires. It should further be ensured that the measurement of external standards, e.g. 99% spectralon standard, is done with the same setup and an additional sapphire as well.

We of course cannot promise any given application will successful or not without seeing spectra. However, several customers have implemented the sapphire process windows for containment with success and we're happy to evaluate solutions for certain requirements.

What's Different Between a SentroPAT Compact and SentroPAT FO with a SentroProbe DR LS?

The SentroPAT FO has a wavelength range of 1100 - 2100 nm with a resolution of NMT 12 nm FWHM. The SentroPAT Compact has a wavelength range of 1100 - 1900 nm with a
resolution of NMT 10 nm FWHM. The wavelength and resolution are the most obvious differences between the two systems, in addition to some differences in signal-to-noise owing to the difference in cooling (SentroPAT FO) versus slight heating (SentroPAT Compact) used to maintain a consistent detector temperature.

Both the SentroPAT FO and SentroPAT Compact are capable instruments. However, for the most challenging applications or relevant absorbance bands are above 1900nm, it may be advisable to look at a SentroPAT FO due to the expanded wavelength range and lower noise. However, many if not most NIR PAT applications in pharmaceuticals can be well served by a SentroPAT Compact
 

Contact

Are you interested in purchasing the SentroPAT Compact or have any questions regarding it? Our sales representative will be happy to help you.

Have questions? I'm here to help—reach out today!
Sebastian Sowinski
Key Account Manager Sentronic GmbH
Have questions? I'm here to help—reach out today!
Owen Rehrauer
President Sentronic US Corp.

Additional Products

Explore our wide range of innovative products designed to meet the diverse needs of pharmaceutical manufacturing.

SentroPAT FO

Diode array NIR analyzer for pharmaceutical powder blending

Discover more
SentroProbe DR LS

Smart probe for applications based on diffuse reflectance

Discover more
SentroPAT DA

Most compact and powerful NIR system for bin blending

Discover more
SentroPAT BU II

High performance system dedicated to monitoring bin blending  

Discover more